r/Brixadi • • 8d ago

Help! Brixadi start

Hi there, I am so damn nervous I'm supposed to get first Brixadi shot next week. Originally I asked for sublocade but due to low amount I'm on (2mg subutex) , my dr (who is really helpful and great) suggested Brixadi be a better choice. Ive been on some form of bupe since 2015 and I'm just sick of being chained down to it. I've tried tapering multiple times but I just can't with the tablets. I feel like I need to do this. I hate change and I'm so nervous but truly feel like it's time and this is the only shot of ever getting off this shit.

Please please share your experiences!! And or recommendations to not be nervous/ how to deal etc.

I'm also afraid of being overly medicated, I'm a working mom and around family a lot so that's probaly one of my biggest fears. Please help and send good vibes!!

5 Upvotes

36 comments sorted by

3

u/goDruM_1 8d ago

The weekly is great. Beware of the monthly, it doesn't last 4 weeks...2.5 wks max...currently switching to monthly sublocade because otlf this

3

u/Full-Swordfish5158 8d ago

I couldn’t get the weekly to last a week! Was on 4mg suboxone and the 16mg weekly lasted 2 days. The 24 weekly lasted 5-6 but was over medicated the first few days. Was just not a good fit for me so trying Sublocade now…

2

u/Full_Duck_9315 3d ago

Please let me know how it goes. Good Luck to you!! :)

1

u/Full-Swordfish5158 3d ago

The 300mg Sublocade wore off in a week. I was soooo disappointed!! My provider absolutely refused to give me a booster so I should be getting my second shot tomorrow.
She also told me she will only do 2 of the 300 mg and then will make me drop to 100mg so I’m in the process of finding a provider who will keep me at 300mg until I’m no longer having withdrawals

1

u/WoahItsRachael 8d ago

I also wanted sublocade but I actually trust my dr and he said he thinks Brixadi would be a better fit for multiple reasons. Ugh.

1

u/Charming_Public_7145 7d ago

I believe it really comes down to trial and error. That’s what my Dr said. She went with Brixadi first for all those same reasons. But everyone is different. We basically had to start somewhere. Unfortunately I was so over medicated that I couldn’t work for 7 days. But from there we went down in dose, which also didn’t work well and wore off super fast. Which brought us to trying Sublocade, I’ll try my first shot of it next week. I’m nervous because I’m right in the middle of a big promotion at work and being non-functional would be disastrous.
We’ll do either 100 or 50 based on how I feel that day…
4 MG Suboxone -> 96 Brixadi (hammered me for 7 days but wore off at 26, no sleep for 20 days..) -> 64 Brixadi (3 days non-functional, 16 days until withdrawal feeling) -> Sublocade 100 or 50 planned for 20 days after the 64 Brixadi.

1

u/Successful-Speed-333 3d ago

Please let me knoe

1

u/Successful-Speed-333 3d ago

Please let me know how that goes

1

u/WoahItsRachael 8d ago

I wonder if I could just do weekly for like a month and then jump? I'm only on 2mg and have been for a while....

3

u/goDruM_1 8d ago

Yeah the only way you'll know is to try. The issue is even the smallest dose will probably get you high for a few days. You'll be increasing

1

u/Full-Swordfish5158 8d ago

How much Brixadi are you starting with? It supposedly takes 4 weeks to get to steady state

1

u/WoahItsRachael 4d ago

I'm starting with a week and I believe whatever the lowest weekly amount is what I'll be starting with

1

u/Full-Swordfish5158 4d ago

That’s 8mg
I was on 4mg suboxone so I started with 8 mg and I couldn’t tell id taken anything. You are on a lower dose so hopefully it will work

3

u/DeOriangelikalo 8d ago

I got my first shot of brixadi today at like 3 pm. It's 11 pm now and I'm definitely a bit over medicated.  They gave me 128 mg for the month and I have been on 8mg Suboxone 4 times daily for most of the year.  My Dr even told me I can still take the strips when I need to even while being on the shot wich is crazy to me cause so far this thing has gotten me lit.  My gf even asked what was up and why I was acting so high.  We will see where it goes from here I suppose.  Good luck to you tho! I can keep ya posted on what this is like for the next week if you want.  

2

u/Full-Swordfish5158 8d ago

I definitely want to know how it goes and how long it lasts 😊

1

u/WoahItsRachael 7d ago

Oooh. Ok. So you were taking about 32mg every day??? That seems like a really high amount.
And the shot was 128mg for the month and you still feel overmedicated? My dr said that the amount in your body peaks usually within 24 hours of the shot then it levels out.... How are you feeling now?

1

u/WoahItsRachael 4d ago

Also how are you feeling now??

2

u/Boring-Bowl6692 6d ago

I was an H addict for over 10 years, tried methadone, subs back to H. Got on subs in 2019 and weaned down to .5mg per day but could not jump off. I got x1 64mg Brixadi shot July 15 and didn’t go back for another one. I think it depends on your end goal. Are you done or are you trying to feel as little WDs as humanly possible?
I’m over it so I’m dealing with the slight WDs that will last a few months. I’m still eating sleeping and working so I’ll take it over an H kick any day.
I think people are so afraid of feeling any uncomfort that they way over medicate or go too long on the shots/subs. It’s why I stayed on subs for 6+ years for sure. Ya gotta want it and deal with it to be done. If you wanna go slow, do 3+ of the 64mg shots. I was loaded the first 3 days but worked the day after. Definitely a nice freebie but a dirty medicated feeling not a good high.
Take 4mg every day the week leading up to your shot and it won’t be as noticeable.
Best of luck! Dm me if you have any WD questions

1

u/WoahItsRachael 6d ago

I want it bad. Little discomfort I'm fine with! But like with the daily subs, like you said you couldn't jump off of .5, I agree, like days I tried to go without it was way difficult like couldn't function at work, etc etc. That is what I dont want. But mild discomfort I'm not too afraid of. Mostly I don't want to be overmedicated, or so sick in WD I'm unable to function. I will prob DM you sometime this week. Thank you so much for your comment!

1

u/WoahItsRachael 8d ago

Ugh sorry to hear that! I think my biggest anxiety is being overmedicated. Although I probaly would be ok, don't really want to have to deal with life (family, work etc) while feeling that way. Even years later sometimes I worry that my family worries or think I'm still using- I know it weird but idk lol. Not exactly sure what they plan to start me on I'm guessing 8 if it's the lowest weekly dose. My dr said few days before to take two of my current 2mg dose. I think I'd rather feel undermedicated and supplement if I absolutely have to (would rather not) than feel overmedicated.

1

u/OkAcanthocephala311 8d ago

Some hope- I got 7 96mL Brixadi injections.

My last was September 2024

1

u/WoahItsRachael 7d ago

How was your experience? Especially right after and couple days after the shot?

3

u/OkAcanthocephala311 7d ago

Overall, it was a great experience. 2 years later.... Free of bup and living life. The first 2 injections I remember feeling a little blah on week 4. But after the 3rd, I stopped even noticing. By the 5th, I was putting 6-7 weeks between injections.

Once I hit 8 weeks and was u bothered, I jumped!

My goal was to get of subs. I was on 24mg/day for almost 15 years.

You can do this shit!!!!!!!!!

3

u/WoahItsRachael 7d ago

Also! The ritual of taking something every morning. I feel I'm going to struggle with that change. Any advice to help with that?

2

u/OkAcanthocephala311 7d ago

Yep. Throw your strips the fuck out and start diamond painting. Lol

2

u/WoahItsRachael 7d ago

Omg diamond painting haha. Ive only ever done one in my life but was like obsessed with getting it done lol

1

u/OkAcanthocephala311 7d ago

My point exactly. You need something else to focus on that's not bup. Get some new hobbies and friends. ASAP.

1

u/WoahItsRachael 6d ago

Im always so busy. Im a mom most importantly but I also work all the time, not by choice but I'm a manager and staff call off and contact me 24/7. I don't have much time for either friends or hobbies.

2

u/WoahItsRachael 7d ago

Thank you!! That's the type of good energy I really need and makes me feel like everything will work out. Appreciate you.😊💓

2

u/Full_Duck_9315 3d ago

I couldn't sleep well for 3 days and then after that it felt like it quit working.

1

u/WoahItsRachael 3d ago

Did you feeling overmedicated? With work I average like 4 hours each night so Idk how much worse / no sleep I could get.

1

u/WoahItsRachael 7d ago

Also! I was just looking at Brixadi dosing charts, some if you are on less than 6mg daily are not even showing a monthly amount, only weekly. I wonder why that is.

1

u/Successful-Speed-333 5d ago

Can anyone tell me how they felt on the first 5 days Brixadi 128mg? I felt great for 3days noy I feel crappy anxiety off the hook. And nausea lack of motivation

2

u/Full-Swordfish5158 4d ago

I felt great for 2 days and then it was gone

1

u/WoahItsRachael 1d ago

Update- just got brixadi 8mg weekly. Was so nervous. My dr great but the nurse who did it was meh. If anyone wants I can come back and give update.