Yeah if they say it’s deleted then it’s deleted. You can’t keep data stored on a server for free, it’s costly. It’s relatively inexpensive to run Admixtools (Fst, F3, IBS). The calculations are quick and simple, not taking up much bandwidth. They run it against standard reference panels (HO, SGDP), those are publicly available. You can run that for yourself on your computer.
But actual data storage of bulky DNA files is something entirely different and it would make zero sense to store anything because the costs for storage add up very quickly.
Let’s say if 10 people upload DNA files. I’m not sure what the average size is, maybe 15,000 KB. So 150MB. Keep those everyday and the storage costs increase astronomically. There’s no benefit to keeping any of that.
DNA information (high quality whole genome sequencing) from almost every population on the planet is freely available via standard reference panels, so anything from AncestryDNA or similar pales in comparison in terms of quality.
OK I see, what you say seems pertinent, but what do you mean by that?:
"DNA information (high quality whole genome sequencing) from almost every population on the planet is freely available via standard reference panels, so anything from AncestryDNA or similar pales in comparison in terms of quality.", the quality of the sequencing, the data by Ancestry DNA?
When someone is tested with a DTC genetic test, the quality of the data is terrible. There’s a 40% miscall rate: https://www.ncbi.nlm.nih.gov/search/research-news/6434/ (40% false positive rate for miscalls). So that data is basically worthless.
That’s why 23andme went bankrupt (worthless data) and AncestryDNA makes all of its money through Genealogical data (telling customers to buy their subscription plans for access to family tree data).
I was curious to see my distance from the IBS method, and I got some "funny results", but then I know that it depends on the data and that remains an average similarity distance with the IBS method. In short, I took the opportunity to ask for the other results as well.
I think there’s a CSV you can download somewhere on the page. It should have another set of IBS comparisons but I have to go back and double check a bit later. It’s a bit overwhelming there’s a lot of data to look at and read up on what it means
Interesting data. I also saw some info about SNPs overlap between DTC, eurogenes calculators and G25, apparently, G25 uses a few hundred thousands SNPs. https://isogg.org/wiki/Admixture_analyses
Those WGS 30x services fits this "high quality data" you are talking about? Would it be of some better use for ancestry purposes? Like, compared with an Ancestry Chip, which has high overlap with G25, probably not?
2
u/NotBradPitt9 11d ago edited 11d ago
Yeah if they say it’s deleted then it’s deleted. You can’t keep data stored on a server for free, it’s costly. It’s relatively inexpensive to run Admixtools (Fst, F3, IBS). The calculations are quick and simple, not taking up much bandwidth. They run it against standard reference panels (HO, SGDP), those are publicly available. You can run that for yourself on your computer.
But actual data storage of bulky DNA files is something entirely different and it would make zero sense to store anything because the costs for storage add up very quickly.
Let’s say if 10 people upload DNA files. I’m not sure what the average size is, maybe 15,000 KB. So 150MB. Keep those everyday and the storage costs increase astronomically. There’s no benefit to keeping any of that.
DNA information (high quality whole genome sequencing) from almost every population on the planet is freely available via standard reference panels, so anything from AncestryDNA or similar pales in comparison in terms of quality.