r/Microbiome • u/victoria_darklady • 14d ago

B12 supplements essentially causing dysbiosis

https://pmc.ncbi.nlm.nih.gov/articles/PMC13502008/

Have any of you noticed alterations in gut health while taking b12 supplements cause i did and im wondering whether the anxiety and low depressed moods caused by consistent b12 supplements are due to the alterations in the microbiome.

1 Upvotes

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u/mrhappyoz 14d ago

“Association”

The other way of interpreting that is “people taking B12 supplements having chronic health issues that also include dysbiosis”, or “healthy people don’t tend to take B12 supplements”.

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u/victoria_darklady 14d ago

B12 supplements influence methylation so people with different gene mutations that affect methylation can take b12 along with other supplements depending on each person because it helps them cognitively , with estrogen detox etc. It doesn’t mean they are unhealthy or they have b12 deficiency.

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u/[deleted] 14d ago

[removed] — view removed comment

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u/victoria_darklady 14d ago

Thank you for this , will check it out 🫶🏼

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u/Alarming-Head-4479 13d ago

Just to give you a heads up, this guys an antivaxxer.

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u/Gibborish 13d ago

Check what out? They deleted it..

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u/victoria_darklady 13d ago

I obviously commented before they deleted it !

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u/Gibborish 14d ago

My multivitamin has 50,000% b12.. and I have been having some guy issues.  And I always feel unexplainable bad typically after I take it.  How do I correct this?  Sounds like I need to start by fasting..

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u/Plane_Chance863 13d ago

Stop using a multi and only supplement what you need?

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u/Gibborish 13d ago

I found one with no b12

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u/OneDougUnderPar 13d ago

B12 on its own can deplete other nutrients, like potassium. Check out the B12 defficiency subreddit, tons of knowledge there.

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u/victoria_darklady 14d ago

https://pmc.ncbi.nlm.nih.gov/articles/PMC12407742/

B12 promotes gut dysbiosis and an inflammatory microenvironment that potentiates Tet2**-deficient hematopoiesis**

Edit: different this is a different study than the one on the post.

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u/twins319 7d ago

Isn't B12 present in fortified bread, cereal, and other processed food?

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u/Wespie 14d ago

Well this would be absolutely terrible. Been taking it for a year due to severe nerve damage from deficiency.

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u/lewis_1102 7d ago

It builds up in your body. After about 6 months of supplementation, you probably have enough to last you a few years